The expressions of B7-H1 and B7-H4 co-stimulatory molecules on dendritic cells in pre-eclampsia
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چکیده
Results The expressions of B7-H1 and B7-H4 molecules were significantly higher on CD1c+ myeloid and BDCA-2+ plasmocytoid DCs in the first trimester of pregnancy when compared to the luteal phase of the ovarian cycle. Moreover, the expressions of B7-H1 molecule on CD1c+ DCs in the second trimester of normal pregnancy were significantly higher when compared to the first trimester. In the third trimester they decreased when compared to the second trimester. The expressions of B7-H1 molecule on CD1c+ myeloid and BDCA-2+ plasmocytoid DCs were significantly lower in pre-eclampsia when compared to healthy third trimester pregnant women.
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